Guillermo`s main PhD publication was published in Nature Cardiovascular Research! He used single-cell RNA sequencing and spatial transcriptomics to analyze the composition of the muscle microenvironment in non-ischemic patients and patients with peripheral artery disease and identified ATF3/ATF4+endothelial cells that exhibit altered angiogenic and immune regulatory profiles during PAD and confirmed that ATF4 signaling in ECs is required for effective ischemia recovery.
A new manuscript detailing enhanced culture conditions for derivation of bovine muscle cells has been published in Advanced Science. This study represents the first paper on cultivated meat from our lab, and has been featured extensively in media outlets. Congratulations to Christine, Adhi and coauthors on this wonderful achievement!
We thank Michèle Oetiker for more than three successful years of dedication and great work as an administrator for the RMB lab team. We wish her all the best for the future!